Indeed, characterization of the infiltrating immune cell populations highlighted that tumors with higher monocytes were also greatly infiltrated with key cells for anti-tumor immunity, such as B-cells, CD8 T-cells, M1 MΦs, and Th1 cells, resulting in an elevated ImmuneScore index and higher presence of immune-reactive cells (Fig. 6b). The gene discussed is CD8A; the disease is neoplasm.