Furthermore, the median expression value of ACTA2-AS1 in COAD tissues was the cut-off value and then divided the tissues into high expression group (n = 41) and low expression group (n = 41), Kaplan–Meier survival analysis suggested that high-ACTA2-AS1 expression was associated with longer survival time in patients with COAD (Fig. 1g). The gene discussed is ACTA2; the disease is colon adenocarcinoma.