The rest are completely unknown for their splicing role in cancer, even though changes in expression of some of them have been shown to play a role in tumour progression, chemosensitivity and metastasis without specifically addressing which splice variant (ATP5C1, BNIP2, FAT1, FNBP1, SEC31A, ANXA6, DNM1, DNM2) [61, 77]. This evidence concerns the gene SEC31A and cancer.