After GPR120 activation by lardoil, GIP secretion increased with a consequent reduction in plasmaglucose levels.21 Furthermore, 1 was able to promote GLP-1 secretion after a long-term supplementation,thus promoting pancreatic insulin secretion and β-cell proliferationin rats.103 GPR120 deficiency impairedmetabolic balance, leading to insulin resistance. The gene discussed is FFAR4; the disease is Insulin resistance.