Increased inflammatory markers such as C-reactive protein, interleukin (IL)-1, IL-6, and tumor necrosis factor (TNF)-α, interstitial cellular adhesion molecule-1, vascular cellular adhesion molecule-1, CD8+T cells, natural killer (NK) cells, and E-selectin are associated with the development of nephropathy in many chronic diseases [3]. The gene discussed is TNF; the disease is kidney disorder.