TP53 and acute myeloid leukemia: Also B56ε has been reported to suppresses p53-independent apoptosis but induces p53-dependent apoptosis (Jin et al., 2010) and a high frequency of PP2A B56ε downregulation is observed in AML cell lines (Cristóbal et al., 2013) that could be associated, at least in part, with p53 deregulation.