Here, IFN-α-conditioned DC (IFN-DC) were monitored within 3D tumor spaces for their ability to infiltrate and engulf collagen-embedded SW620 colorectal cancer cells treated with a combination of drugs (Romidepsin and IFN-α) with respect to untreated (Parlato et al., 2017). This evidence concerns the gene IFNA1 and colorectal cancer.