Our data demonstrated that MRTF-A depletion impedes EGF- and serum-induced cancer cell migration, which is consistent with previous results implicating MRTF-A as an oncogene in leukemia (Ma et al., 2001), pancreatic cancer (Song et al., 2016), and lung cancer (Cheng et al., 2015). This evidence concerns the gene MRTFA and familial pancreatic carcinoma.