LATS2 and neoplasm: Finally, based on the establishment of xenograft models, it was proved that mass and quantity of the tumour in the exo-circ_100395 group were remarkably dropped as compared to the exo-NC group, which were markedly elevated in the exo-circ_100395 + miR-141-3p and exo-circ_100395 + si-LATS2 groups as compared to the exo-circ_100395 (Figures 7A–C).