Given that hsa-miR-103a-3p responded to hypoxia and targeted argonaute 1 (AGO1) to promote angiogenesis (Chen et al., 2013), and EXO-miR-103a increases angiogenesis in gastric cancer targeting c-MYB (Liang et al., 2015), downregulation of exosomal hsa-miR-103a-3p in the BPD group is likely to suppress fetal angiogenesis. The gene discussed is AGO1; the disease is bronchopulmonary dysplasia.