The top-ten highly expressed genes (HK1, CSE1L, TNPO1, SEC61A1, RPS15A, SFPQ, EIF4A2, UTP6, CAPZB, and MDH2) in esophageal cancer were further selected to analyze the differential expression in the esophageal cancer patient cohort in TCGA database using UCSC Xena (Figure 6E). Here, SEC61A1 is linked to esophageal cancer.