Statistical analyses suggested that GINS4 expression was significantly correlated with age (P = 0.009), gender (P = 0.001), AFP level (P = 0.049), T classification (P = 0.007), TNM stage (P = 0.011), histologic grade (P < 0.001), the status of residual tumor (P = 0.023), and relapse (P = 0.018) as well as vital status (P = 0.004). The gene discussed is GINS4; the disease is neoplasm.