ERBB2 and breast cancer: A multiple logistic regression analysis of 1,779 patients with primary invasive breast cancer in Italy showed that premenopausal women with WC ≥ 80 cm were prone to luminal B breast cancer, including HER2-negative (OR = 2.55, 95% CI 1.53-4.24) and HER2-positive women (OR = 2.11, 95% CI 1.03-4.35), whereas women with BMI ≥ 25 kg/m2 (OR = 3.04, 95% CI 1.43-6.43) were significantly related to TNBC compared with other subtypes (13).