Pathology confirmed the diagnosis of left breast invasive ductal carcinoma with two separate foci, the larger being a 44 mm tumour at stage pT2, pN1a (grade III) and with positive ER and PR statuses, and the smaller tumour measuring 7 mm at stage pT1b, pN0 (grade II) with triple-negative status. This evidence concerns the gene ESR1 and neoplasm.