Phlorizin can effectively reduce body weight, redress disturbance of glucose and lipid metabolism, and educe dangerous factors of obesity; it may play a role by downregulating the level of mTOR and its phosphorylation, up‐regulating GβL, Raptor expression, improving glucose, and lipid metabolism in liver tissue (Guo, 2013). Here, MTOR is linked to obesity due to melanocortin 4 receptor deficiency.