BCL2 and cancer: Anticancer agents frequently act via induced of apoptosis in cancer cells, and this has been demonstrated as an important mechanism by which other peptide types exert anticancer activity; rapeseed protein source peptide has been shown to induce apoptosis in HUVEC cells via downregulation of Bcl‐2 and increased cleaved caspase‐3 and Bax expression (Xu et al., 2018).