It has been reported that between 2 and 45% of mouse tissue’s transcriptome display a circadian rhythm (Duffield et al., 2002; Panda et al., 2002; Kornmann et al., 2007; Perelis et al., 2015), and that these clock-controlled genes (CCGs) contribute to multiple physiological and pathological processes including signal transduction, cancer and immune system disorders, and so on (Jagannath et al., 2017). This evidence concerns the gene TAF1 and immune system disorder.