CCR7 and B-cell chronic lymphocytic leukemia: The canonical view of CCR7 as a LN homing receptor of CLL cells has been up-dated thanks to studies revealing CCR7 as a key mediator of interstitial migration towards PCs and other locations where CLL cells cross-talk with accessory cells and have access to trophic factors which promote tumor growth and progression, including CCR7’s own ligands.