IFNG and tuberculosis: Here we found that SQV treatment induces higher levels of T-cell-secreted IFN-γ in a context that mimics bacteria replication during active TB (Figure 3E). This increased secretion of IFN-γ may have a dual effect: (1) activation of Mø to a more bactericidal state and, (2) indirectly contributing to a decreased IL-1β secretion.