MPO and eosinophilic granulomatosis with polyangiitis: A recent GWAS for EGPA including 676 EGPA cases and 6,809 controls in European populations showed that HLA-DQ was strongly associated with EGPA at genome-wide significance (P = 1.2 × 10−20,OR = 2.01), especially MPO -ANCA EGPA (P = 1.1 × 10−28, OR = 5.68) (16).