CTLA4 and neoplasm: In line with this study, Vetizou et al. (10) also found that Bacteroidales played an important role in the immunostimulatory effects of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade by promoting the maturation of intratumoral dendritic cells and with a TH1 response detected in the lymph nodes of the draining tumor.