Some of their structural and regulator components, including non-receptor cytoplasmic tyrosine kinase cSrc, Focal adhesion kinase (Fak), Paxillin (Pax), Tyrosine-protein phosphatase non-receptor type 12 (PTP-PEST), and integrins have been associated with the spread of glioblastoma cells (8–11). Here, PTPN12 is linked to glioblastoma.