The lack of IL-10 resulted more severe myocardial fibrosis Verma et al. (2012) the administration of rIL-10 improved cardiac remodeling Krishnamurthy et al. (2009) IL-10 treatment decreased the myocardial inflammation in mice with autoimmune myocarditis Zimmermann et al. (2012). This evidence concerns the gene IL10 and Myocardial fibrosis.