On top of exhibiting direct antiviral effects, medicinal plants with reported anti-inflammatory activities may have pleiotropic roles in COVID-19 management as the elevation of inflammatory markers such as interleukin (IL)-6, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) has been associated with severe disease with worse outcomes among COVID-19 patients, most likely related to cytokine storm (Zeng et al., 2020). This evidence concerns the gene IL6 and COVID-19.