CXCR2 and familial pancreatic carcinoma: Since neutrophils express C-X-C chemokine receptor–type 2 (CXCR2), they are attracted by ligands like CXCL1/IL-8, CXCL2, and CXCL5, released in pancreatitis and pancreatic cancer (Saurer et al., 2000; Steele et al., 2016; Najder et al., 2018; Wu et al., 2019; Zhang et al., 2020).