CASP3 and Stroke: Western blotting results revealed significant increases in DAPK1, caspase-3, and cleaved caspase-3 levels in PIT-stroke and Anta-miR-124 + PIT-stroke mice compared to that in sham mice; and significant decreases in DAPK1, caspase-3, and cleaved caspase-3 levels in Ago-miR-124 + PIT-stroke mice compared to that in PIT-stroke mice (Figures 4D,E).