MAOB and Alzheimer disease: The activity of MAO-B is also increased in brains of AD patients relative to age-matched controls, while MAO-A activity has been reported to be unchanged or increased depending on the brain regions under investigation (Adolfsson et al. 1980; Jossan et al. 1991; Oreland and Gottfries 1986; Quartey et al. 2018; Reinikainen et al. 1988; Saura et al. 1994; Sherif et al. 1992; Sparks et al. 1991).