Interestingly, both MT2A and LATS2 were significantly down-regulated in the lung cancer samples compared to the normal control in the TCGA LUAD cohort (Figure 1B), but the univariate cox analysis of overall survival revealed that both MT2A and LATS2 were the risk genes with a HR of more than 1 (Figure 4), which was validated by our Kaplan Meier survival curve analysis (Figure 5). This evidence concerns the gene LATS2 and lung cancer.