HOXA11 and Parkinson disease: It was discovered that compared with the PD+si-NC group, the spontaneous motor activity was increased, the time to fall off the rotard rod was extended, and the time staying on the bevel was increased after downregulating HOXA11-AS, indicating that repressing HOXA11-AS1 mitigated neurological deficits of PD mice (P <0.05, Figure 6A).