The tentative risk factors included the test result of systolic hypertension, erythrocytosis, higher alanine transaminase (ALT) level, higher serum creatinine level, and hypertriglyceridemia; a present diagnosis of diabetes mellitus; past history of otolaryngological diseases, stroke, hepatitis, and arthritis including rheumatoid arthritis; and lifestyles of alcoholic beverage intake, current smoking, skipping breakfast and midnight snack eating, preference of salty tastes, a slow gait, longer daily sleeping, and frequent night-time awakening. The gene discussed is GPT; the disease is diabetes mellitus.