Some new blood index are under study, LDH, neutrophil–lymphocyte ratio (NLR), absolute eosinophil count, monocyte count and myeloid-derived suppressor cells (MDSCs), T-cell markers and soluble PD-L1 (sPD-L1), B cell-antibody markers, soluble CD25 (sCD25), blood tumor mutational burden (bTMB) and so on. The gene discussed is CD274; the disease is neoplasm.