While previous studies have indicated that cross-talk between SOX4 and TGFβ can mediate activation of canonical Smad signaling in order to induce EMT17,19,20, the role of SOX4 in regulating noncanonical TGFβ signaling in cancer, or in TNBC or basal-like breast cancer specifically, has not been reported. This evidence concerns the gene SOX4 and breast cancer.