Arginine-rich DPRs also increased the incidence of mitochondria pausing within or at the end of a processive movement (Fig. 3, B and D), as was observed in human sMNs treated with these peptides or derived from C9-ALS/FTD patients (Figs. 1C and 2, E and F). This evidence concerns the gene C9 and frontotemporal dementia.