Among the 16 FLT3-TKD mutant AML patients, 11 cases had fusion genes (four cases with AML1-ETO, two cases with MLL-AF9, one case with AML1-MDS1, one case with DEC-CAN, one case with BCR-ABL, one case with CBFB-MYH11, and one case with MLL-TMX2 -CTNND1) (Fig. 2c, d). This evidence concerns the gene MECOM and acute myeloid leukemia.