IL33 and atopic eczema: For example, a study using an animal model of atopic dermatitis revealed that increased TSLP expression directly stimulated Group 2 Innate Lymphoid Cells (ILC2s), which are key regulators and effectors in type 2 immunity, and enhanced the production of interleukin-33 (IL-33) and interleukin-25 (IL-25) [68, 88, 89].