CD4 and Immunodeficiency: This implies that A. indica extract did not affect CD4+ T cell IFN-γ and IL-2 responses following stimulation with Gag. However, variation in immune deficiency between the viral load < 1000 copies/ ml and viral load > 1000 copies/ ml study groups could account for  differences in downmodulation of immune activation seen following testing with A. indica (Fig. 5).