In this regard, a significant decrease in tumour size was reported in athymic nude mice bearing carcinoembryonic antigen (CEA)-positive orthotopic pancreatic cancers treated with 100 μg of anti-CEA-IR700 and exposed to 270 J/cm2 NIR light (690 nm) 24 h later (Maawy et al., 2015). The gene discussed is CEACAM5; the disease is neoplasm.