Laboratory evaluation revealed that most dialyzed ESKD patients with COVID-19during hospitalization presented anemia (77.3%), hyperfibrinogenemia (77.3%),hyperferritinemia (70.5%), increased D-dimer levels (56.8%), lymphopenia(54.5%), and increased CRP levels (52.3%), depicting a more profoundinflammatory and thrombotic profile. The gene discussed is CRP; the disease is anemia (phenotype).