When including age (as a continuous variable) in addition to fibulin-2 expression along with tumour diameter, histologic grade and lymph node status in an alternative multivariate model, fibulin-2 was significant (HR = 1.88; 95% CI 1.00–3.54; p = 0.050) in addition to lymph node status (HR = 3.27; 95% CI 1.71–6.27; p<0.0005), whereas tumour diameter (p = 0.56), histologic grade (p = 0.09) and age (p = 0.10) were not significant in this series. Here, FBLN2 is linked to neoplasm.