In addition, we found that among the 13 genes in the prognosis model, 8 genes have been studied and proved to promote HCC progress, including CBX2 [9], SLC1A5 [10], LDHA [11], GSR [12], GPC1 [13], GDI2 [14], ADAMTS5 [15] and WEE1 [16]. The gene discussed is ADAMTS5; the disease is hepatocellular carcinoma.