During the preparation of this manuscript, a family with a pediatric HHT case with PAVMs harboring a p.[Tyr354ArgfsTer15];[Tyr354ArgfsTer15] GDF2 mutation was reported, although measurements of BMP9/10 levels and activity were not undertaken (Liu et al., 2020). This evidence concerns the gene GDF2 and hereditary hemorrhagic telangiectasia.