In addition to tumor-infiltrating immune cells, immune-related gene sets such as RIPOR2, DAAM2, SORBS1, and CXCL8 (Mei et al., 2020), or LTA, TFRC, TYK2, DLL4, CSK, JUND, NFATC4, SBDS, FLT1, IL17RD, IL3RA, SDC1, PLAU (Ding et al., 2020), were proposed as prognostic genes to stratify CESC patients. The gene discussed is TFRC; the disease is cervical squamous cell carcinoma.