MMP2 and endothelial dysfunction: The soluble cells' adhesion molecules, such as sICAM-1, sVCAM-1, sE-selectin, and metalloproteinases MMP-2 and MMP-9, given the expression of endothelial dysfunction and plaque alteration, are increased in both diabetics and psoriatics compared with controls, with the exception of sE-selectin increased only in psoriatics compared with controls.