Signal transducer and activator of transcription 1 has been identified to promote cell adhesion, invasion, and migration in a variety of cancers (Greenwood et al., 2012) supported by most studies using adhesion assay, wound healing assay, transwell assay, and Western blot analyses to detect invasion markers such as matrix metallopeptidase 2 (MMP-2) and MMP-9 (Zhang and Zou, 2015). The gene discussed is STAT1; the disease is cancer.