CD274 and pancreatic adenocarcinoma: In the PFI analysis, according to the results of KM analysis, the subjects with a high CD274 expression had poor PFI relative to those with a low CD274 expression in PAAD (p = 0.027, Supplementary Figure 4C); whereas the subjects having an increased CD274 expression showed superior PFI than those having a decreased CD274 expression in CHOL (p = 0.025, Figure 2C), as shown in Supplementary Figure 3; high PDCD1LG2 predicted superior prognosis for CHOL (p = 0.005, Figure 2E) and LIHC (p = 0.003, Supplementary Figure 3E).