VEGFA and cancer: Various neutrophil-related elements (such as tumor-associated neutrophils, vascular endothelial growth factor, and neutrophil extracellular traps) may promote mutations leading to tumorigenesis and tumor cell proliferation, contribute to tumor-related angiogenesis, induce cancer cells to metastasize, inhibit T-cell activity against tumor cells, and increase adhesion between circulating tumor cells and organs (15–19).