Except for the robust association between Ccl28 and MDSC fraction, Ccl28 (Figure 5G) was also observed positive correlation with immune suppressive signatures (Supplementary Figure 4E), including tumor-associated macrophages, ICI resistance, exosome assemble, and EMT process, highlighting the potential power in altering immune microenvironment of Ccl28 is worth further investigated. Here, CCL28 is linked to neoplasm.