OGDH and cancer: In addition, other two proteins, which were also connected with ENO1 in our network, might play important roles in MM: Oxoglutarate dehydrogenase (OGDH) – it is a subunit of an enzymatic complex that participates in the Krebs cycles, and it was also found that several cancer cells depend on this protein for growth and survival (41); Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2B1) – it influences pre-RNA process, and mRNA metabolism and transport; Shen et al.