A study conducted by Moreau-Marquis et al. showed that the expression of the most common mutation of CFTR-ΔF508-CFTR mutation in airway cells increases iron release, which enhances biofilm formation, thereby increasing resistance of P. aeruginosa to tobramycin (Tb); therefore, the amount of Tb required to eliminate P. aeruginosa biofilms on airway cells is 10 times more than the amount achievable in the lungs of cystic fibrosis patients [12]. This evidence concerns the gene CFTR and cystic fibrosis.