Similarly, Xiang et al. (2020) found that circ-Foxo3 was highly expressed in Gastric cancer cell lines and confirmed the existence of the circ-Foxo3/miR-143-3p/USP44 axis via a series of assays based on bioinformatics analysis Kong et al. (2020) identified that circ-Foxo3, which targets SLC25A15, combined miR-29a-3p to promote the proliferation, invasion, apoptosis and tumorigenesis of prostate cancer. This evidence concerns the gene FOXO3 and Familial prostate cancer.